Section A (50%): Essay
Answer ONE question from this section
- 1. Analyse and evaluate how genome-wide DNA sequencing and integrated genomic analysis has advanced the understanding and treatment of human cancer
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- 2. Analyse and evaluate the involvement of DNA methylation in human genetic disease.
Section B (50%): Essay
Answer ONE question from this section
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- 1. How has the analysis of genetic mutants been used in the study of DNA repair pathways? Use specific examples in your answer
- 2. Explain why specific mammalian cell types naturally induce DNA double strand breaks in their genome How is the recombination pathway that is used in the repair of these induced breaks important to the biological function of the break?
6744-BLGY3152 OTLA August 2022
