Explain any five parameters that are critical to control drug release from a PLGA-based long-acting drug delivery system.
[100%]
Please write your answer within the lines above and below this sentence (you may delete this text)
(a) Describe the differences between top-down and bottom-up approaches in nanoparticle production, including an example of each approach.
[30%]
(b) Discuss the advantages non-viral vectors have over viral vectors for nucleic acid delivery.
[30%]
(c) Discuss the composition, structure, and nucleic acid release mechanism of the Pfizer BioNTech vaccine for COVID-19 that have led to the positive immune response in humans.
[40%]