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Question: Mike is a 23-year-old white male admitted for severe depression.......

13 Feb 2023,11:33 PM


Mike is a 23-year-old white male admitted for severe depression. He has a history of bipolar disorder and is currently taking valproate (Depakote) 500 mg XR daily. His psychiatrist ordered LFT's to follow the valproate therapy. LFT's were abnormal: ALT 1178 u/L, AST 746 u/L. The patient was asymptomatic. He denies fever, abdominal pain, nausea, vomiting, and is not visibly jaundiced.
He denies using other medication or alcohol but admits using illicit IV drugs starting about 8 weeks ago and continuing to present. He never had a blood transfusion. Aside from valproate (Depakote), he is presently taking clonazepam 1 mg prn and fluoxetine (Prozac) 40 mg daily.

Other blood work: Direct bili 1 mg/dL, alk phos 188 u/L, anti-HCV negative on hospital day 1, positive on day 3. HCV-RNA PCR positive. Hep A, B, and D markers negative.

Patient diagnosis: Acute Hepatitis C.

Answer the following 2 questions:
1. What is the pathophysiology of Hepatitis C?
2. What impact would the medications have on his liver function?


Requirements:
- Minimum of 250 words (one double-spaced page is sufficient). There is no need for a lengthy introduction or conclusion.
- 2 scholarly sources within the last 5 years (one may be your textbook).
- APA 7th edition Student Format
- Insert hyperlinks in your reference page
- All discussion posts must be submitted through Turnitin. Any post with more than a 20% similarity score will have one opportunity to revise and resubmit their work.
- If this week’s discussion post consists of a case study, you may mention the case study in your answer to the question(s), but do not write them verbatim. 

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