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Question: When a suspect cannot be excluded from contributing to a crime scene, what are some of the challenges a DNA analyst can have if only Y-STR profile from the crime scene is available?

31 Oct 2022,6:26 PM

 

In the mitochondrial DNA sequence, within the control region, what are the sub-regions more commonly analyzed in forensic sciences? (4 points).
When a suspect cannot be excluded from contributing to a crime scene, what are some of the challenges a DNA analyst can have if only Y-STR profile from the crime scene is available? Or in other words, "Describe in your own words, one limitation of Y-STRs when comparing Y-STR profiles between members of the same family" (4 points)
What are some of the situations where mtDNA may be used and some of the benefits of doing so? (4 points)
What keeps forensic laboratories from performing more nonhuman DNA testing? (4 points)
What are some of the challenges with trying to determine a reliable Y-STR profile frequency estimate when a suspect cannot be excluded from contributing to a crime scene sample? Or in other words "What are some of the challenges with trying to calculate the uniqueness of a Y-STR profile - what are the limitations of the counting method?" (5 points).
Why are disaster victim identifications more challenging than missing persons investigations? (4 points)

Expert answer

 

If a Y-STR profile is the only DNA evidence available from a crime scene, it can be difficult for a DNA analyst to determine whether or not a particular suspect can be excluded as a contributor. This is because the Y-STR profile will only provide information on the individual's paternal line, and cannot give any information on other potential relatives who may also share that same Y-STR profile. In addition, the Y-STR profile will not give any information on the individual's ethnicity, which can make it difficult to compare against known population databases. As such, it is important for DNA analysts to consider all of the available evidence when trying to determine whether or not a particular suspect can be excluded from contributing to a crime scene.

 

In other words,

 

One limitation of Y-STRs when comparing Y-STR profiles between members of the same family is that they can only provide information on the individual's paternal line. This means that other relatives who share the same Y-STR profile will not be identified, and the ethnicity of the individual cannot be determined. As such, DNA analysts must take care to consider all of the available evidence when trying to determine whether or not a particular suspect can be excluded from contributing to a crime scene.

 

If a DNA analyst is working with a Y-STR profile from a crime scene, one of the challenges they may face is that many members of the same family will have very similar Y-STR profiles. This can make it difficult to determine whether or not a particular individual could have contributed to the crime scene. Additionally, because the Y chromosome is passed down from father to son, any mutations that occur in the Y-STRs will also be passed down in this manner. This means that over time, the Y-STR profiles of different members of a family can become quite diverse. As a result, it is possible for two individuals who are related to each other to have quite different Y-STR profiles.If a DNA analyst is working with a Y-STR profile from a crime scene, one of the challenges they may face is that many members of the same family will have very similar Y-STR profiles. This can make it difficult to determine whether or not a particular individual could have contributed to the crime scene. Additionally, because the Y chromosome is passed down from father to son, any mutations that occur in the Y-STRs will also be passed down in this manner. This means that over time, the Y-STR profiles of different members of a family can become quite diverse. As a result, it is possible for two individuals who are related to each other to have quite different Y-STR profiles.

 

If a Y-STR profile is the only DNA evidence available from a crime scene, it can be difficult for a DNA analyst to determine whether or not a particular suspect can be excluded as a contributor. This is because the Y-STR profile will only provide information on the individual's paternal line, and cannot give any information on other potential relatives who may also share that same Y-STR profile. In addition, the Y-STR profile will not give any information on the individual's ethnicity, which can make it difficult to compare against known population databases. As such, it is important for DNA analysts to consider all of the available evidence when trying to determine whether or not a particular suspect can be excluded from contributing to a crime scene.

 

One limitation of Y-STRs when comparing Y-STR profiles between members of the same family is that they can only provide information on the individual's paternal line. This means that other relatives who share the same Y-STR profile will not be identified, and the ethnicity of the individual cannot be determined. As such, DNA analysts must take care to consider all of the available evidence when trying to determine whether or not a particular suspect can be excluded from contributing to a crime scene.

If a Y-STR profile is the only DNA evidence available from a crime scene, it can be difficult for a DNA analyst to determine whether or not a particular suspect can be excluded as a contributor. This is because the Y-STR profile will only provide information on the individual's paternal line, and cannot give any information on other potential relatives who may also share that same Y-STR profile. In addition, the Y-STR profile will not give any information on the individual's ethnicity, which can make it difficult to compare against known population databases. As such, it is important for DNA analysts to consider all of the available evidence when trying to determine whether or not a particular suspect can be excluded from contributing to a crime scene.

 

One limitation of Y-STRs when comparing Y-STR profiles between members of the same family is that they can only provide information on the individual's paternal line. This means that other relatives who share the same Y-STR profile will not be identified, and the ethnicity of the individual cannot be determined. As such, DNA analysts must take care to consider all of the available evidence when trying to determine whether or not a particular suspect can be excluded from contributing to a crime scene.

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